- Perfect Clear: Crystal Mother
Beat the boss "Crystal Mother" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Battleswarm
Beat the boss "Battleswarm" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: WallMaster
Beat the boss "WallMaster" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Mirror
Beat the boss "Mirror" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Backfire
Beat the boss "Backfire" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: ShrapnelRose
Beat the boss "ShrapnelRose" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: LadyStaccato
Beat the boss "LadyStaccato" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Labyrinth
Beat the boss " Labyrinth" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Aggressor
Beat the boss "Aggressor" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Centrifuge
Beat the boss "Centrifuge" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Vestige
Beat the boss "Vestige" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Fusillade
Beat the boss "Fusillade" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Aberration
Beat the boss "Aberration" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: The Warden
Beat the boss "The Warden" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Terminus
Beat the boss "Terminus" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Invader
Beat the boss "Invader" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Periphery
Beat the boss "Periphery" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Metal Legion
Beat the boss "Metal Legion" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Sunder
Beat the boss "Sunder" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: The Humbled
Beat the boss "The Humbled" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: Valor
Beat the boss "Valor" with a perfect clear, also not using missiles or consumables.
- Perfect Clear: All Bosses
Beat each base game boss with a perfect clear, also not using missiles or consumables.
- Perfect Clear: All Mini Bosses
Beat each miniboss with a perfect clear, also not using missiles or consumables.
- Kill Final Boss With Deep Blue Mech
Kill the "final" boss while using the Deep Blue mech.
- Kill Final Boss With Green Envy Mech
Kill the "final" boss while using the Green Envy mech.
- Kill Final Boss With Flame Tank Mech
Kill the "final" boss while using the Flame Tank mech.
- Kill Final Boss With Indigo Dipole Mech
Kill the "final" boss while using the Indigo Dipole mech.
- Kill Final Boss With Redshift Mech
Kill the "final" boss while using the Redshift mech.
- Kill Final Boss With White Gloss Mech
Kill the "final" boss while using the White Gloss mech.
- Kill Final Boss With Humble Mech
Kill the "final" boss while using the Humble mech.
- Kill Final Boss With Alpha Mech
Kill the "final" boss while using the Alpha mech.
- Kill Final Boss With Penumbra Mech
Kill the "final" boss while using the Penumbra mech.
- Kill Final Boss With All Mechs
Kill the "final" boss with each of the original six mechs.
- Kill Super-Final Boss With Deep Blue Mech
Kill the "real" final boss with the Deep Blue mech.
- Kill Super-Final Boss With Green Envy Mech
Kill the "real" final boss with the Green Envy mech.
- Kill Super-Final Boss With Flame Tank Mech
Kill the "real" final boss with the Flame Tank mech.
- Kill Super-Final Boss With Indigo Dipole Mec
Kill the "real" final boss with the Indigo Dipole mech.
- Kill Super-Final Boss With Redshift Mech
Kill the "real" final boss with the Redshift mech.
- Kill Super-Final Boss With White Gloss Mech
Kill the "real" final boss with the White Gloss mech.
- Kill Super-Final Boss With Humble Mech
Kill the "real" final boss with the Humble mech.
- Kill Super-Final Boss With Alpha Mech
Kill the "real" final boss with the Alpha mech.
- Kill Super-Final Boss With Penumbra Mech
Kill the "real" final boss with the Penumbra mech.
- Kill Super-Final Boss With All Mechs
Kill the "real" final boss with each of the original six mechs.
- Incredibility: Life Harvester
Pick up the Incredibility Life Harvester on the first floor, never drop it, and win the run.
- Incredibility: Consummate Consumer
Pick up the Incredibility Consummate Consumer on the first floor, never drop it, and win the run.
- Incredibility: Minimalist
Pick up the Incredibility Minimalist on the first floor, never drop it, and win the run.
- Incredibility: The One
Pick up the Incredibility The One on the first floor, never drop it, and win the run.
- Incredibility: Magnetic Personality
Pick up the Incredibility Magnetic Personality on the first floor, never drop it, and win the run.
- Incredibility: Jaywalker
Pick up the Incredibility Jaywalker on the first floor, never drop it, and win the run.
- Incredibility: Confidence
Pick up the Incredibility Confidence on the first floor, never drop it, and win the run.
- Incredibility: Risky Assas
Pick up the Incredibility Risky Assassin on the first floor, never drop it, and win the run.
- Incredibility: The Creator
Pick up the Incredibility The Creator on the first floor, never drop it, and win the run.
- Incredibility: Lilliputian
Pick up the Incredibility Lilliputians on the first floor, never drop it, and win the run.
- Incredibility: High Speed
Pick up the Incredibility High Speed Danger on the first floor, never drop it, and win the run.
- Incredibility: Corrupting Power
Pick up the Incredibility Corrupting Power on the first floor, never drop it, and win the run.
- Clear All Condemned Bosses
Beat each condemned boss.
- Do You Actually Have Any Cheese?
Kill a shopkeeper.
- An Entourage Befitting A Hydral
Have 5 familiars at once.
- Safari
Kill at least one of each non-boss enemy.
- Unlock All Items
Satisfy the unlock conditions for all items.
- Find All Items
Actually find (pick up) every single item.
- Untouchable
Complete a floor with no damage.
- Conspicuous Nonconsumption
Complete a run without buying any items.
- Noncommittal
Complete a run without picking up any attachment items.